National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't N.I.H. Extramural Phosphorylation / drug effects gene expression regulation / drug effects reactive oxygen species / metabolism* neurons / drug effects fatty acids / metabolism mitochondria / drug effects neurons / metabolism* membrane potential mitochondrial / drug effects feeding behavior / drug effects synapses / metabolism hypothalamus / metabolism hypothalamus / drug effects neuropeptide y / metabolism* mitochondria / physiology zane b andrews agouti-related protein / genetics agouti-related protein / metabolism* ghrelin / metabolism* neuropeptide y / genetics pmid:18668043 pmc4101536 doi:10.1038/nature07181 zhong-wu liu sabrina diano carnitine o-palmitoyltransferase / metabolism ghrelin / pharmacology ion channels / genetics ion channels / metabolism* mitochondrial / physiology mitochondrial proteins / genetics mitochondrial proteins / metabolism* synapses / drug effects uncoupling protein 2