Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase
Abstract
Wapl is a new regulator of sister chromatid resolution and promotes release of cohesin from chromosomes by directly interacting with its regulatory subunits.
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
N.I.H.
Extramural
cell line
Nuclear Proteins / metabolism*
hela cells
cell cycle proteins / metabolism*
cell nucleus / metabolism
carrier proteins / metabolism*
chromosomal proteins
non-histone / metabolism*
protein subunits / metabolism
dimerization
chromatids / metabolism*
pmid:17112726
pmc1850625
doi:10.1016/j.cub.2006.10.061
rita gandhi
peter j gillespie
tatsuya hirano
oncogene proteins / metabolism*
prometaphase*
proto-oncogene proteins
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274051
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