Fetal Programming: Prenatal Testosterone Treatment Leads to Follicular Persistence/Luteal Defects; Partial Restoration of Ovarian Function by Cyclic Progesterone Treatment
Manikkam, Mohan;Steckler, Teresa L.;Welch, Kathleen B.;Inskeep, E. Keith;Padmanabhan, Vasantha;
endocrinology2006Vol. 147pp. 1997-2007
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mohan2006endocrinologyfetal
Abstract
Prenatal testosterone (T) excess during midgestation leads to estrous cycle defects and polycystic ovaries in sheep. We hypothesized that follicular persistence