Healthy and preeclamptic pregnancies show differences in Guanylate-Binding Protein-1 plasma levels
Abstract
The large interferon-inducible anti-angiogenic pro-inflammatory GTPase Guanylate Binding Protein-1 (GBP-1) is produced and secreted by activated endothelial cells and is highly induced by inflammatory cytokines and inhibited by angiogenic growth factors. During pregnancy a generalized mild inflammat …
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