An auxin-based degron system for the rapid depletion of proteins in nonplant cells
Abstract
Plants have evolved a unique system in which the plant hormone auxin directly induces rapid degradation of the AUX/IAA family of transcription repressors by a specific form of the SCF E3 ubiquitin ligase. Other eukaryotes lack the auxin response but share the SCF degradation pathway, allowing us to …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
cell line
Chickens
green fluorescent proteins / metabolism
proteins / metabolism*
saccharomyces cerevisiae / metabolism
indoleacetic acids / metabolism*
pmid:19915560
doi:10.1038/nmeth.1401
kohei nishimura
tatsuo fukagawa
masato kanemaki
skp cullin f-box protein ligases / metabolism
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273940
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