The RSC chromatin-remodeling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the Cdc14 phosphatase
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The RSC chromatin-remodeling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the Cdc14 phosphatase

Valentina Rossio, Elena Galati, Matteo Ferrari, Achille Pellicioli, Takashi Sutani, Katsuhiko Shirahige, Giovanna Lucchini, Simonetta Piatti;Valentina Rossio;Elena Galati;Matteo Ferrari;Achille Pellicioli;Takashi Sutani;Katsuhiko Shirahige;Giovanna Lucchini;Simonetta Piatti;
the journal of cell biology 2010 Vol. 191 pp. 981-
137
piatti2010thethe

Abstract

Upon prolonged activation of the spindle assembly checkpoint, cells escape from mitosis through a mechanism called adaptation or mitotic slippage, which is thought to underlie the resistance of cancer cells to antimitotic drugs. We show that, in budding ...

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DOI:
10.1083/jcb.201007025
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC299516...

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