Nonhuman primate models of polycystic ovary syndrome
David H Abbott, Lindsey E Nicol, Jon E Levine, Ning Xu, Mark O Goodarzi, Daniel A Dumesic;David H Abbott;Lindsey E Nicol;Jon E Levine;Ning Xu;Mark O Goodarzi;Daniel A Dumesic;
molecular and cellular endocrinology2013Vol. 373pp. 21-
148
dumesic2013molecularnonhuman
Abstract
With close genomic and phenotypic similarity to humans, nonhuman primate models provide comprehensive epigenetic mimics of polycystic ovary syndrome (PCOS), suggesting early life targeting for prevention. Fetal exposure to testosterone (T), of all nonhuman ...