Nonhuman primate models of polycystic ovary syndrome

Nonhuman primate models of polycystic ovary syndrome

David H Abbott, Lindsey E Nicol, Jon E Levine, Ning Xu, Mark O Goodarzi, Daniel A Dumesic;David H Abbott;Lindsey E Nicol;Jon E Levine;Ning Xu;Mark O Goodarzi;Daniel A Dumesic;
molecular and cellular endocrinology 2013 Vol. 373 pp. 21-
148
dumesic2013molecularnonhuman

Abstract

With close genomic and phenotypic similarity to humans, nonhuman primate models provide comprehensive epigenetic mimics of polycystic ovary syndrome (PCOS), suggesting early life targeting for prevention. Fetal exposure to testosterone (T), of all nonhuman ...

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