Glioma cells require one-carbon metabolism to survive glutamine starvation
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Glioma cells require one-carbon metabolism to survive glutamine starvation

Kazuhiro Tanaka, Takashi Sasayama, Hiroaki Nagashima, Yasuhiro Irino, Masatomo Takahashi, Yoshihiro Izumi, Takiko Uno, Naoko Satoh, Akane Kitta, Katsusuke Kyotani, Yuichi Fujita, Mitsuru Hashiguchi, Tomoaki Nakai, Masaaki Kohta, Yoichi Uozumi, Masakazu Shinohara, Kohkichi Hosoda, Takeshi Bamba, Eiji Kohmura;Kazuhiro Tanaka;Takashi Sasayama;Hiroaki Nagashima;Yasuhiro Irino;Masatomo Takahashi;Yoshihiro Izumi;Takiko Uno;Naoko Satoh;Akane Kitta;Katsusuke Kyotani;Yuichi Fujita;Mitsuru Hashiguchi;Tomoaki Nakai;Masaaki Kohta;Yoichi Uozumi;Masakazu Shinohara;Kohkichi Hosoda;Takeshi Bamba;Eiji Kohmura;
acta neuropathologica communications 2021 Vol. 9 pp. -
144
kohmura2021actaglioma

Abstract

Cancer cells optimize nutrient utilization to supply energetic and biosynthetic pathways. This metabolic process also includes redox maintenance and epigenetic regulation through nucleic acid and protein methylation, which enhance tumorigenicity and clinical ...

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DOI:
10.1186/s40478-020-01114-1
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC78145...

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