Lenalidomide and dexamethasone with or without clarithromycin in patients with multiple myeloma ineligible for autologous transplant: a randomized trial

Lenalidomide and dexamethasone with or without clarithromycin in patients with multiple myeloma ineligible for autologous transplant: a randomized trial

Puig N;Hernández MT;Rosiñol L;González E;de Arriba F;Oriol A;González-Calle V;Escalante F;de la Rubia J;Gironella M;Ríos R;García-Sánchez R;Arguiñano JM;Alegre A;Martín J;Gutiérrez NC;Calasanz MJ;Martín ML;Couto MDC;Casanova M;Arnao M;Pérez-Persona E;Garzón S;González MS;Martín-Sánchez G;Ocio EM;Coleman M;Encinas C;Vale AM;Teruel AI;Cortés-Rodríguez M;Paiva B;Cedena MT;San-Miguel JF;Lahuerta JJ;Bladé J;Niesvizky R;Mateos MV;;
blood cancer journal 2021 Vol. 11 pp. -
174
n2021bloodlenalidomide

Abstract

Although case-control analyses have suggested an additive value with the association of clarithromycin to continuous lenalidomide and dexamethasone (Rd), there are not phase III trials confirming these results. In this phase III trial, 286 patients with MM ineligible for ASCT received Rd with or wit …

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