Prospective Multicenter International Surveillance of Azole Resistance inAspergillus fumigatus
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Prospective Multicenter International Surveillance of Azole Resistance inAspergillus fumigatus

J.W.M. Van Der Linden,Maiken Cavling Arendrup,Adilia Warris,Katrien Lagrou,Herve Pelloux,Philippe Hauser,E. Chryssanthou,Emilia Mellado,Sarah Kidd,Anna Maria Tortorano,Eric Dannaoui,P. Gaustad,J.W. Baddley,A. Uekötter,C. Lass-Flörl,Nikolay Klimko,C.B. Moore,David Denning,J. Van Der Linden Et Al.,C. Kibbler,S. Arikan-Akdagli,David Andes,J. Meletiadis,L. Naumiuk,M. Nucci,Willem Melchers,Paul Verweij;J.W.M. Van Der Linden;Maiken Cavling Arendrup;Adilia Warris;Katrien Lagrou;Herve Pelloux;Philippe Hauser;E. Chryssanthou;Emilia Mellado;Sarah Kidd;Anna Maria Tortorano;Eric Dannaoui;P. Gaustad;J.W. Baddley;A. Uekötter;C. Lass-Flörl;Nikolay Klimko;C.B. Moore;David Denning;J. Van Der Linden Et Al.;C. Kibbler;S. Arikan-Akdagli;David Andes;J. Meletiadis;L. Naumiuk;M. Nucci;Willem Melchers;Paul Verweij;
emerging infectious diseases 2015 Vol. 21 pp. 1041-1044
209
verweij2015emergingprospective

Abstract

To investigate azole resistance in clinical Aspergillus isolates, we conducted prospective multicenter international surveillance. A total of 3,788 Aspergillus isolates were screened in 22 centers from 19 countries. Azole-resistant A. fumigatus was more frequently found (3.2% prevalence) than previously acknowledged, causing resistant invasive and noninvasive aspergillosis and severely compromising clinical use of azoles.

Keywords

prevalence azole resistance Aspergillus surveillance international aspergillosis antimicrobial resistance fungi

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DOI:
10.3201/eid2106.140717
URL:
https://sciprofiles.com/publication/view/d20256bf0...

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ID: 273470
Ref Key: verweij2015emergingprospective
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