The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition
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The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition

David S Yee, Yaxiong Tang, Xuesen Li, Zhongbo Liu, Yi Guo, Samia Ghaffar, Peter McQueen, Dash Atreya, Jun Xie, Anne R Simoneau, Bang H Hoang, Xiaolin Zi;David S Yee;Yaxiong Tang;Xuesen Li;Zhongbo Liu;Yi Guo;Samia Ghaffar;Peter McQueen;Dash Atreya;Jun Xie;Anne R Simoneau;Bang H Hoang;Xiaolin Zi;
molecular cancer 2010 Vol. 9 pp. 162-
192
zi2010molecularthe

Abstract

Aberrations in the Wnt pathway have been reported to be involved in the metastasis of prostate cancer (PCa) to bone. We investigated the effect and underlying mechanism of a naturally-occurring Wnt inhibitor, WIF1, on the growth and cellular invasiveness ...

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DOI:
10.1186/1476-4598-9-162
URL:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC290733...

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