Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation
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Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation

Thomas Schlange, Yutaka Matsuda, Susanne Lienhard, Alexandre Huber, Nancy E Hynes;Thomas Schlange;Yutaka Matsuda;Susanne Lienhard;Alexandre Huber;Nancy E Hynes;
breast cancer research : bcr 2007 Vol. 9 pp. R63-
137
hynes2007breastautocrine

Abstract

De-regulation of the wingless and integration site growth factor (WNT) signaling pathway via mutations in APC and Axin, proteins that target β-catenin for destruction, have been linked to various types of human cancer. These genetic alterations ...

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DOI:
10.1186/bcr1769
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC224265...

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