Untargeted Molecular Analysis of Exhaled Breath as a Diagnostic Test for Ventilator-Associated Lower Respiratory Tract Infections (BreathDx)

Untargeted Molecular Analysis of Exhaled Breath as a Diagnostic Test for Ventilator-Associated Lower Respiratory Tract Infections (BreathDx)

van Oort PM;Nijsen TM;White IR;Knobel HH;Felton T;Rattray N;Lawal O;Bulut M;Ahmed W;Artigas A;Povoa PR;Martin-Loeches I;Weda H;Goodacre R;Schultz MJ;Dark PM;Fowler SJ;Bos LD; ;;
Thorax 2021 pp. -
252
pm2021thoraxuntargeted

Abstract

Patients suspected of ventilator-associated lower respiratory tract infections (VA-LRTIs) commonly receive broad-spectrum antimicrobial therapy unnecessarily. We tested whether exhaled breath analysis can discriminate between patients suspected of VA-LRTI with confirmed infection, from patients with …

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