Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro
Abstract
The promoter selectivity factor Sp1 often cooperates with other enhancer-binding proteins to activate transcription. To study the molecular underpinnings of these regulatory events, we have reconstituted in vitro the synergy observed in vivo between Sp1 and the sterol-regulated factor SREBP-1a at th …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
genetic
Drosophila
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
models
research support
non-u.s. gov't
u.s. gov't
P.H.S.
Receptors
DNA-Binding Proteins / physiology*
Nuclear Proteins / physiology*
Promoter Regions
hela cells
drug synergism
transcription factors*
sterol regulatory element binding protein 1
chromatin / physiology*
ccaat-enhancer-binding proteins*
LDL / genetics
r tjian
transcription factor tfiid
transcriptional activation*
pmid:9765204
pmc317191
doi:10.1101/gad.12.19.3020
a m näär
p a beaurang
helix-loop-helix motifs / physiology*
leucine zippers / physiology*
sp1 transcription factor / physiology*
transcription factors
tfii / physiology
Access
Citation
ID:
273297
References
Blockchain Verification
Account:
NFT Contract Address:
0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
273297
Unique Identifier:
Network:
Scimatic Chain (ID: 481)
Loading...
Blockchain Readiness Checklist
Authors
Abstract
Journal Name
Year
Title
Creates 1,000,000 NFT tokens for this article
Token Features:
- ERC-1155 Standard NFT
- 1 Million Supply per Article
- Transferable via MetaMask
- Permanent Blockchain Record
Scan with Saymatik Web3.0 Wallet