A novel embryonic poly(A) binding protein, ePAB, regulates mRNA deadenylation in Xenopus egg extracts

A novel embryonic poly(A) binding protein, ePAB, regulates mRNA deadenylation in Xenopus egg extracts

Gia K. Voeltz, Julina Ongkasuwan, Nancy Standart, Joan A. Steitz;Gia K. Voeltz;Julina Ongkasuwan;Nancy Standart;Joan A. Steitz;
genes & development 2001 Vol. 15 pp. 774-
115
steitz2001genesa

Abstract

An in vitro system that recapitulates the in vivo effect of AU-rich elements (AREs) on mRNA deadenylation has been developed from Xenopus activated egg extracts. ARE-mediated deadenylation is uncoupled from mRNA body decay, and the rate of deadenylation ...

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