Hepatitis B virus-host interactions and novel targets for viral cure

Hepatitis B virus-host interactions and novel targets for viral cure

Ligat G;Verrier ER;Nassal M;Baumert TF;;
current opinion in virology 2021 Vol. 49 pp. -
123
g2021currenthepatitis

Abstract

Chronic infection with HBV is a major cause of advanced liver disease and hepatocellular carcinoma. Nucleos(t)ide analogues effectively control HBV replication but viral cure is rare. Hence treatment has often to be administered for an indefinite duration, increasing the risk for selection of drug r …

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