A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability.

A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability.

A B Sachs, R W Davis, R D Kornberg;A B Sachs;R W Davis;R D Kornberg;
molecular and cellular biology 1987 Vol. 7 pp. 3268-
109
kornberg1987moleculara

Abstract

The poly(A)-binding protein (PAB) gene of Saccharomyces cerevisiae is essential for cell growth. A 66-amino acid polypeptide containing half of a repeated N-terminal domain can replace the entire protein in vivo. Neither an octapeptide sequence conserved ...

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