Construction of synthetic nucleoli in human cells reveals how a major functional nuclear domain is formed and propagated through cell division

Construction of synthetic nucleoli in human cells reveals how a major functional nuclear domain is formed and propagated through cell division

Alice Grob, Christine Colleran, Brian McStay;Alice Grob;Christine Colleran;Brian McStay;
genes & development 2014 Vol. 28 pp. 220-
126
mcstay2014genesconstruction

Abstract

Human cell nuclei are functionally organized into structurally stable yet dynamic bodies whose cell cycle inheritance is poorly understood. Here, we investigate the biogenesis and propagation of nucleoli, sites of ribosome biogenesis and key regulators ...

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10.1101/gad.234591.113
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