Use of post-mortem human synaptosomes for studies of metabolism and transmitter amino acid release
Abstract
Synaptosomes have been prepared from human brain obtained at autopsies carried out up to 24 h postmortem (p.m.). They showed generally good retention of morphology, as well as accumulation of tissue potassium and linear rates of oxygen uptake. In response to veratrine depolarization they showed incr …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
adult
female
male
aged
middle aged
microscopy
potassium / metabolism
electron
glutamic acid
synapses / metabolism
glutamates / metabolism
pmid:6131398
doi:10.1016/0304-3940(82)90392-5
j a hardy
p r dodd
j a edwardson
amino acids / metabolism*
aspartic acid / metabolism
frontal lobe / metabolism*
synaptic transmission*
synaptosomes / metabolism*
gamma-aminobutyric acid / metabolism
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272829
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