Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling
Abstract
G protein-coupled receptors (GPCRs) are seven transmembrane proteins that form the largest single family of integral membrane receptors. GPCRs transduce information provided by extracellular stimuli into intracellular second messengers via their coupling to heterotrimeric G proteins and the subseque …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
Receptors
signal transduction / physiology*
cell surface / physiology*
pmid:11171937
s s ferguson
arrestins / physiology
endocytosis / physiology*
gtp-binding proteins / physiology*
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