Ancient human genome sequence of an extinct Palaeo-Eskimo
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Ancient human genome sequence of an extinct Palaeo-Eskimo

Rasmussen M;Li Y;Lindgreen S;Pedersen JS;Albrechtsen A;Moltke I;Metspalu M;Metspalu E;Kivisild T;Gupta R;Bertalan M;Nielsen K;Gilbert MT;Wang Y;Raghavan M;Campos PF;Kamp HM;Wilson AS;Gledhill A;Tridico S;Bunce M;Lorenzen ED;Binladen J;Guo X;Zhao J;Zhang X;Zhang H;Li Z;Chen M;Orlando L;Kristiansen K;Bak M;Tommerup N;Bendixen C;Pierre TL;Grønnow B;Meldgaard M;Andreasen C;Fedorova SA;Osipova LP;Higham TF;Ramsey CB;Hansen TV;Nielsen FC;Crawford MH;Brunak S;Sicheritz-Pontén T;Villems R;Nielsen R;Krogh A;Wang J;Willerslev E;;
Nature 2010 Vol. 463 pp. -
269
m2010natureancient

Abstract

We report here the genome sequence of an ancient human. Obtained from approximately 4,000-year-old permafrost-preserved hair, the genome represents a male individual from the first known culture to settle in Greenland. Sequenced to an average depth of 20x, we recover 79% of the diploid genome, an am …

Keywords

National Center for Biotechnology Information NCBI NLM MEDLINE Genetics humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't non-p.h.s. male DNA Sequence Analysis genome phenotype human / genetics* Phylogeny Genotype Polymorphism biological* historical article history genomics population ancient cryopreservation* single nucleotide / genetics pmid:20148029 pmc3951495 doi:10.1038/nature08835 morten rasmussen yingrui li eske willerslev emigration and immigration / history extinction greenland hair inuits / genetics* siberia / ethnology

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