Marine-Derived Penicillium Species as Producers of Cytotoxic Metabolites
Sen Liu,Mingzhi Su,Shao-Jiang Song,Jee H. Jung;Sen Liu;Mingzhi Su;Shao-Jiang Song;Jee H. Jung;
Marine drugs2017Vol. 15pp. 329-
203
jung2017marinemarine-derived
Abstract
Since the discovery of penicillin, Penicillium has become one of the most attractive fungal genera for the production of bioactive molecules. Marine-derived Penicillium has provided numerous excellent pharmaceutical leads over the past decades. In this review, we focused on the cytotoxic metabolites * (* Cytotoxic potency was referred to five different levels in this review, extraordinary (IC50/LD50: