Essential roles of BMPR-IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis
Abstract
Hair differentiation and growth are controlled by complex reciprocal signaling between epithelial and mesenchymal cells. To better understand the requirement and molecular mechanism of BMP signaling in hair follicle development, we performed genetic analyses of bone morphogenetic protein receptor 1A …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
u.s. gov't
P.H.S.
signal transduction*
Receptors
bone morphogenetic protein receptors
type i
mutant strains
protein-serine-threonine kinases / metabolism
trans-activators / genetics
morphogenesis
protein-serine-threonine kinases / physiology*
cell division / physiology*
pmid:15124223
doi:10.1002/gene.20021
kin ming kwan
allen g li
richard r behringer
cell differentiation / physiology*
hair / growth & development*
growth factor / metabolism
growth factor / physiology*
skin neoplasms / pathology*
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272490
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