Opposing polymerase-deadenylase activities regulate cytoplasmic polyadenylation
Abstract
Cytoplasmic polyadenylation is one mechanism that regulates translation in early animal development. In Xenopus oocytes, polyadenylation of dormant mRNAs, including cyclin B1, is controlled by the cis-acting cytoplasmic polyadenylation element (CPE) and hexanucleotide AAUAAA through associations wit …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
N.I.H.
Extramural
Base Sequence
Molecular Sequence Data
ribonucleases / metabolism*
phosphorylation
cell nucleus / metabolism
xenopus
poly a / metabolism
joel d richter
oocytes / metabolism
pmid:17052452
doi:10.1016/j.molcel.2006.08.016
jong heon kim
cyclin b / metabolism
cyclin b1
cytoplasm / metabolism
dna-directed dna polymerase / metabolism*
polyadenylation
polynucleotide adenylyltransferase / metabolism
xenopus laevis / metabolism
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272488
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