Ultrastructural localization of tyrosine hydroxylase in noradrenergic neurons of brain
Pickel VM;Joh TH;Reis DJ;;
Proceedings of the National Academy of Sciences of the United States of America1975Vol. 72pp. -
208
vm1975proceedingsultrastructural
Abstract
Tyrosine hydroxylase (EC 1.14.16.2), the enzyme catalyzing the rate-limiting step in catecholamine biosynthesis, was localized by electron microscopy within noradrenergic neurons of the nucleus locus coeruleus of the rat brain with a specific antibody to tyrosine hydroxylase labeled by the peroxidas …