Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial

Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial

Palumbo A;Bringhen S;Caravita T;Merla E;Capparella V;Callea V;Cangialosi C;Grasso M;Rossini F;Galli M;Catalano L;Zamagni E;Petrucci MT;De Stefano V;Ceccarelli M;Ambrosini MT;Avonto I;Falco P;Ciccone G;Liberati AM;Musto P;Boccadoro M; ;;
Lancet (London, England) 2006 Vol. 367 pp. -
231
a2006lancetoral

Abstract

Oral MPT is an effective first-line treatment for elderly patients with multiple myeloma. Anticoagulant prophylaxis reduces frequency of thrombosis. Longer follow-up is needed to assess effect on overall survival.

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