Neuropeptide Y receptor in cultured vascular smooth muscle cells: ligand binding and increase in cytosolic free Ca2+
Abstract
We have previously shown that neuropeptide Y (NPY) increases cytosolic free Ca2+ concentration [( Ca2+]i) in porcine aortic smooth muscle cells. In this study, specific NPY receptor binding sites were identified in the cells by use of [125I]Bolton-Hunter NPY [( 125I]BH-NPY). Binding was to a single …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
Comparative Study
cell line
swine
muscle
binding
competitive
neuropeptide y / metabolism*
peptide fragments / metabolism
smooth
pmid:2090091
s mihara
y shigeri
m fujimoto
calcium / metabolism*
cytosol / metabolism*
vascular / metabolism*
neuropeptide y / pharmacology
pancreatic polypeptide / metabolism
pancreatic polypeptide / pharmacology
peptide fragments / pharmacology
succinimides
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272160
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