Intranasal Granulocyte-Macrophage Colony-Stimulating Factor Reduces the Aspergillus Burden in an Immunosuppressed Murine Model of Pulmonary Aspergillosis
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Intranasal Granulocyte-Macrophage Colony-Stimulating Factor Reduces the Aspergillus Burden in an Immunosuppressed Murine Model of Pulmonary Aspergillosis

Gerardo Quezada, Nadezhda V. Koshkina, Patrick Zweidler-McKay, Zichao Zhou, Dimitrios P. Kontoyiannis, Eugenie S. Kleinerman;Gerardo Quezada;Nadezhda V. Koshkina;Patrick Zweidler-McKay;Zichao Zhou;Dimitrios P. Kontoyiannis;Eugenie S. Kleinerman;
Antimicrobial agents and chemotherapy 2008 Vol. 52 pp. 716-
122
kleinerman2008antimicrobialintranasal

Abstract

We demonstrated that intranasal granulocyte-macrophage colony-stimulating factor given to immunosuppressed mice infected with pulmonary aspergillosis resulted in a sixfold reduction in the lung fungal burden compared to the result for saline-treated mice ...

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DOI:
10.1128/AAC.00760-07
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC22247...

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ID: 272067
Ref Key: kleinerman2008antimicrobialintranasal
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