Function and biological roles of the Dickkopf family of Wnt modulators
Abstract
Dickkopf (Dkk) genes comprise an evolutionary conserved small gene family of four members (Dkk1-4) and a unique Dkk3-related gene, Dkkl1 (soggy). They encode secreted proteins that typically antagonize Wnt/beta-catenin signaling, by inhibiting the Wnt coreceptors Lrp5 and 6. Additionally, Dkks are h …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
models
research support
non-u.s. gov't
conserved sequence
neoplasms / metabolism
biological
signal transduction
wnt proteins / physiology*
cell lineage
xenopus
xenopus proteins / physiology*
wnt proteins / metabolism
pmid:17143291
doi:10.1038/sj.onc.1210054
c niehrs
body patterning
intercellular signaling peptides and proteins / physiology*
ldl-receptor related proteins / metabolism
low density lipoprotein receptor-related protein-6
Citation
ID:
271927
References
Blockchain Verification
Account:
NFT Contract Address:
0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
271927
Unique Identifier:
Network:
Scimatic Chain (ID: 481)
Loading...
Blockchain Readiness Checklist
Authors
Abstract
Journal Name
Year
Title
Creates 1,000,000 NFT tokens for this article
Token Features:
- ERC-1155 Standard NFT
- 1 Million Supply per Article
- Transferable via MetaMask
- Permanent Blockchain Record
Scan with Saymatik Web3.0 Wallet