Hypothermic Neuronal Rescue from Infection-Sensitised Hypoxic-Ischaemic Brain Injury Is Pathogen Dependent
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Hypothermic Neuronal Rescue from Infection-Sensitised Hypoxic-Ischaemic Brain Injury Is Pathogen Dependent

Mari Falck;Damjan Osredkar;Elke Maes;Torun Flatebø;Thomas Ragnar Wood;Hemmen Sabir;Marianne Thoresen;
Developmental Neuroscience 2017 Vol. 39 pp. 238-247
129
falck2017developmentalhypothermic

Abstract

Perinatal infection increases the vulnerability of the neonatal brain to hypoxic-ischaemic (HI) injury. Hypothermia treatment (HT) does not provide neuroprotection after pre-insult inflammatory sensitisation by lipopolysaccharide (LPS), a gram-negative bacterial wall constituent. However, early-onset sepsis in term babies is caused by gram-positive

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developmental neuroscience 2017 vol. 39 no. 1-4 276577

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http://dx.doi.org/10.1159/000455838

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ID: 271923
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