Acquisition of HLA-DR and costimulatory molecules by T cells from allogeneic antigen presenting cells
Abstract
There is accumulating evidence that cell surface molecules may be transferred between cells during an encounter. The aim of these experiments was to determine whether transfer of allogeneic material to T cells could influence human alloresponses. CD4(+) cells were cocultured with M1 cell (human fibr …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
Cells
Cultured
Antigens
polymers / pharmacology
transfection
formaldehyde / pharmacology
t-lymphocytes / immunology*
dendritic cells / immunology
fibroblasts / drug effects
coculture techniques
membrane glycoproteins / genetics
hla-dr antigens / immunology*
antigen-presenting cells / immunology*
pmid:15943619
doi:10.1111/j.1600-6143.2005.00916.x
david s game
nicola j rogers
robert i lechler
antibodies / pharmacology
cd / genetics
cd / immunology*
b7-1 antigen / genetics
b7-1 antigen / immunology*
b7-2 antigen
cd58 antigens / immunology
fibroblasts / immunology
hla-dr antigens / genetics
membrane glycoproteins / immunology*
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271815
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