miR-181c-3p and -5p promotes high-glucose-induced dysfunction in human umbilical vein endothelial cells by regulating leukemia inhibitory factor
Abstract
Diabetes mellitus is a chronic metabolic disease with high blood glucose level and closely related to endothelial dysfunction, an important factor in the pathogenesis of vascular changes. Several miRNAs have been reported to be altered in a diabetic environment including miR-181c. In the article, we …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
adult
female
male
aged
middle aged
Apoptosis / drug effects
Base Sequence
diabetes mellitus
oxidative stress / drug effects
apoptosis / genetics
type 2 / metabolism
type 2 / genetics
type 2 / pathology
micrornas / genetics*
pmid:29605252
doi:10.1016/j.ijbiomac.2018.03.173
xinghua shen
yunling li
xiuping bai
glucose / pharmacology*
human umbilical vein endothelial cells / cytology
human umbilical vein endothelial cells / drug effects*
human umbilical vein endothelial cells / metabolism
leukemia inhibitory factor / genetics*
oxidative stress / genetics
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271786
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