Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5
Abstract
Women with polycystic ovary syndrome (PCOS) have high circulating androgens, thought to originate from ovaries and adrenals, and frequently suffer from the metabolic syndrome including obesity. However, serum androgens are positively associated with body mass index (BMI) not only in PCOS, but also i …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
adult
female
middle aged
Cells
Cultured
body mass index
Adipose Tissue / metabolism*
cell differentiation
cell proliferation
obesity / metabolism*
Androstenedione / metabolism
testosterone / biosynthesis
pmid:15531721
doi:10.1677/joe.1.05762
marcus quinkler
binayak sinha
wiebke arlt
17-hydroxysteroid dehydrogenases / metabolism*
androgens / biosynthesis*
isoenzymes / metabolism*
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271735
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