Tumor Suppressor Pten Inhibits Nuclear Accumulation of β-Catenin and T Cell/Lymphoid Enhancer Factor 1–Mediated Transcriptional Activation
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Tumor Suppressor Pten Inhibits Nuclear Accumulation of β-Catenin and T Cell/Lymphoid Enhancer Factor 1–Mediated Transcriptional Activation

Sujata Persad, Armelle A.Troussard, Timothy R. McPhee, David J. Mulholland, Shoukat Dedhar;Sujata Persad;Armelle A.Troussard;Timothy R. McPhee;David J. Mulholland;Shoukat Dedhar;
the journal of cell biology 2001 Vol. 153 pp. 1161-
184
dedhar2001thetumor

Abstract

β-Catenin is a protein that plays a role in intercellular adhesion as well as in the regulation of gene expression. The latter role of β-catenin is associated with its oncogenic properties due to the loss of expression or inactivation ...

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DOI:
10.1083/jcb.153.6.1161
URL:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC219201...

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ID: 271728
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