Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites
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Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites

Robert E. Johnson, Carlos A. Torres-Ramos, Tadahide Izumi, Sankar Mitra, Satya Prakash, Louise Prakash;Robert E. Johnson;Carlos A. Torres-Ramos;Tadahide Izumi;Sankar Mitra;Satya Prakash;Louise Prakash;
genes & development 1998 Vol. 12 pp. 3137-
109
prakash1998genesidentification

Abstract

Abasic (AP) sites arise in DNA through spontaneous base loss and enzymatic removal of damaged bases. APN1 encodes the major AP-endonuclease of Saccharomyces cerevisiae. Human HAP1 (REF1) encodes the major AP endonuclease which, in addition to its role ...

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DOI:
10.1101/gad.12.19.3137
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC317187...

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