HoxD cluster scanning deletions identify multiple defects leading to paralysis in the mouse mutant Ironside
Basile Tarchini, Thi Hanh Nguyen Huynh, Greg A. Cox, Denis Duboule;Basile Tarchini;Thi Hanh Nguyen Huynh;Greg A. Cox;Denis Duboule;
genes & development2005Vol. 19pp. 2862-
98
duboule2005geneshoxd
Abstract
A spontaneous semidominant mutation (Ironside, Irn) was isolated in mice, leading to severe hindlimb paralysis following multiple deletions in cis at the HoxD locus. To understand its cellular and molecular etiology, we embarked on a comparative analysis ...