HoxD cluster scanning deletions identify multiple defects leading to paralysis in the mouse mutant Ironside

HoxD cluster scanning deletions identify multiple defects leading to paralysis in the mouse mutant Ironside

Basile Tarchini, Thi Hanh Nguyen Huynh, Greg A. Cox, Denis Duboule;Basile Tarchini;Thi Hanh Nguyen Huynh;Greg A. Cox;Denis Duboule;
genes & development 2005 Vol. 19 pp. 2862-
98
duboule2005geneshoxd

Abstract

A spontaneous semidominant mutation (Ironside, Irn) was isolated in mice, leading to severe hindlimb paralysis following multiple deletions in cis at the HoxD locus. To understand its cellular and molecular etiology, we embarked on a comparative analysis ...

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10.1101/gad.351105
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