Asia grew in the Late Permian by the collision of a number of micro-continents. Syn- to post-collisional magmatism occurred along the continental collision zones . In this study, we report two types of granitic rocks, garnet granite (Grt granite) and orthopyroxene granite (Opx granite), from the Kontum massif, central Vietnam, which is situated on the continental collision zone between the South China and Indochina cratons. These granitic rocks were formed at ca. 250 Ma when high-temperature (HT) and ultrahigh-temperature (UHT) metamorphism took place in the same zone. Based on the petrological and geochemical features compared with previously reported experimental results, garnet-bearing granite is derived from pelitic gneisses by partial melting, whereas orthopyroxene-bearing granite is produced by the partial melting of garnet-bearing mafic granulites. We inferred that a significantly high-geothermal gradient is required to produce Vietnamese granitic magmatism and related HT to UHT metamorphism. This geotherm may be attributed to upwelling mantle plume beneath the Kontum massif during the Late Permian.