Features of Variable Number of Tandem Repeats in Yersinia pestis and the Development of a Hierarchical Genotyping Scheme

Features of Variable Number of Tandem Repeats in Yersinia pestis and the Development of a Hierarchical Genotyping Scheme

Li Y;Cui Y;Cui B;Yan Y;Yang X;Wang H;Qi Z;Zhang Q;Xiao X;Guo Z;Ma C;Wang J;Song Y;Yang R;;
PloS one 2013 Vol. 8 pp. -
273
y2013plosfeatures

Abstract

Appropriate selection of target loci reduces the impact of homoplasies caused by the rapid mutation rates of VNTR loci. The optimized "14+12" loci are highly discriminative in genotyping and source-tracing Y. pestis for molecular epidemiological or microbial forensic investigations with less time an …

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