Spread of an Inactive Form of Caspase-12 in Humans Is Due to Recent Positive Selection
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Spread of an Inactive Form of Caspase-12 in Humans Is Due to Recent Positive Selection

Yali  Xue, Allan  Daly, Bryndis  Yngvadottir, Mengning  Liu, Graham  Coop, Yuseob  Kim, Pardis  Sabeti, Yuan  Chen, Jim  Stalker, Elizabeth  Huckle, John  Burton, Steven  Leonard, Jane  Rogers, Chris  Tyler-Smith;Yali  Xue;Allan  Daly;Bryndis  Yngvadottir;Mengning  Liu;Graham  Coop;Yuseob  Kim;Pardis  Sabeti;Yuan  Chen;Jim  Stalker;Elizabeth  Huckle;John  Burton;Steven  Leonard;Jane  Rogers;Chris  Tyler-Smith;
American journal of human genetics 2006 Vol. 78 pp. 659-
133
tyler-smith2006americanspread

Abstract

The human caspase-12 gene is polymorphic for the presence or absence of a stop codon, which results in the occurrence of both active (ancestral) and inactive (derived) forms of the gene in the population. It has been shown elsewhere that carriers of the ...

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DOI:
10.1086/503116
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC142470...

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