Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects
Abstract
Exercise increases insulin sensitivity in both normal subjects and the insulin-resistant offspring of diabetic parents because of a twofold increase in insulin-stimulated glycogen synthesis in muscle, due to an increase in insulin-stimulated glucose transport-phosphorylation.
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
adult
female
male
P.H.S.
Glucose / metabolism*
Active
diabetes mellitus
insulin resistance / physiology*
insulin / metabolism
insulin secretion
exercise / physiology
phosphorylation
physical fitness / physiology*
muscle
biological transport
type 2 / genetics
glucose clamp technique
skeletal / metabolism*
pmid:8857019
doi:10.1056/nejm199610313351804
g perseghin
t b price
g i shulman
glucose-6-phosphate / metabolism
glycogen / biosynthesis*
Citation
ID:
271263
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