Bench-to-bedside review: Citrate for continuous renal replacement therapy, from science to practice
Oudemans-van Straaten HM;Ostermann M;;
critical care (london, england)2012Vol. 16pp. -
143
hm2012criticalbench-to-bedside
Abstract
To prevent clotting in the extracorporeal circuit during continuous renal replacement therapy (CRRT) anticoagulation is required. Heparin is still the most commonly used anticoagulant. However, heparins increase the risk of bleeding, especially in critically ill patients. Evidence has accumulated th …