Effect of levosimendan on estimated glomerular filtration rate in hospitalized patients with decompensated heart failure and renal dysfunction
Abstract
A 24-h infusion with levosimendan transiently improved the renal dysfunction compared with placebo in patients with DHF, and its beneficial effects persisted for at least 14 days after the initiation of treatment.
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
China
humans
pubmed abstract
nih
national institutes of health
national library of medicine
treatment outcome
female
male
aged
middle aged
Prospective Studies
80 and over
linear models
Randomized Controlled Trial
Double-Blind Method
chi-square distribution
time factors
analysis of variance
intravenous
hospitalization*
biomarkers / blood
infusions
natriuretic peptide
brain / blood
heart rate / drug effects
ventricular function
left / drug effects
heart failure / complications
heart failure / diagnosis
heart failure / drug therapy*
simendan
hydrazones / therapeutic use*
pyridazines / therapeutic use*
cardiotonic agents / therapeutic use*
pmid:23490237
doi:10.1111/1755-5922.12001
zhi-qiang hou
zhao-xia sun
de-ya shang
blood pressure / drug effects
cardiotonic agents / administration & dosage
glomerular filtration rate / drug effects*
heart failure / blood
heart failure / physiopathology
hydrazones / administration & dosage
kidney diseases / blood
kidney diseases / complications
kidney diseases / physiopathology*
pyridazines / administration & dosage
stroke volume
urination / drug effects
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Citation
ID:
270971
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