Drosophila PTB promotes formation of high-order RNP particles and represses oskar translation

Drosophila PTB promotes formation of high-order RNP particles and represses oskar translation

Florence Besse, Sonia López de Quinto, Virginie Marchand, Alvar Trucco, Anne Ephrussi;Florence Besse;Sonia López de Quinto;Virginie Marchand;Alvar Trucco;Anne Ephrussi;
genes & development 2009 Vol. 23 pp. 195-
79
ephrussi2009genes drosophila

Abstract

Local translation of asymmetrically enriched mRNAs is a powerful mechanism for functional polarization of the cell. In Drosophila, exclusive accumulation of Oskar protein at the posterior pole of the oocyte is essential for development of the future embryo. ...

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