A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat
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A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat

Vanessa Brès, Nathan Gomes, Loni Pickle, Katherine A. Jones;Vanessa Brès;Nathan Gomes;Loni Pickle;Katherine A. Jones;
genes & development 2005 Vol. 19 pp. 1211-
132
jones2005genesa

Abstract

HIV-1 Tat binds human CyclinT1 and recruits the CDK9/P-TEFb complex to the viral TAR RNA in a step that links RNA polymerase II (RNAPII) C-terminal domain (CTD) Ser 2 phosphorylation with transcription elongation. Previous studies have suggested a connection ...

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DOI:
10.1101/gad.1291705
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC113200...

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