Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation
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Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation

Andrey Korshunov, Konstantin Okonechnikov, Felix Schmitt-Hoffner, Marina Ryzhova, Felix Sahm, Damian Stichel, Daniel Schrimpf, David E. Reuss, Philipp Sievers, Abigail Kora Suwala, Ella Kumirova, Olga Zheludkova, Andrey Golanov, David T. W. Jones, Stefan M. Pfister, Marcel Kool, Andreas von Deimling;Andrey Korshunov;Konstantin Okonechnikov;Felix Schmitt-Hoffner;Marina Ryzhova;Felix Sahm;Damian Stichel;Daniel Schrimpf;David E. Reuss;Philipp Sievers;Abigail Kora Suwala;Ella Kumirova;Olga Zheludkova;Andrey Golanov;David T. W. Jones;Stefan M. Pfister;Marcel Kool;Andreas von Deimling;
acta neuropathologica communications 2021 Vol. 9 pp. -
148
deimling2021actamolecular

Abstract

Primitive neuroectodermal tumors of the central nervous system (CNS-PNETs) are highly malignant neoplasms posing diagnostic challenge due to a lack of defining molecular markers. CNS neuroblastoma with forkhead box R2 (FOXR2) activation (CNS_NBL) emerged ...

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DOI:
10.1186/s40478-021-01118-5
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC78606...

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