The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes - Nature Medicine

The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes - Nature Medicine

Belgardt, Bengt-Frederik;Ahmed, Kashan;Spranger, Martina;Latreille, Mathieu;Denzler, Remy;Kondratiuk, Nadiia;von Meyenn, Ferdinand;Villena, Felipe Nunez;Herrmanns, Karolin;Bosco, Domenico;Kerr-Conte, Julie;Pattou, Francois;Rülicke, Thomas;Stoffel, Markus;Belgardt, Bengt-Frederik;Ahmed, Kashan;Spranger, Martina;Latreille, Mathieu;Denzler, Remy;Kondratiuk, Nadiia;von Meyenn, Ferdinand;Villena, Felipe Nunez;Herrmanns, Karolin;Bosco, Domenico;Kerr-Conte, Julie;Pattou, Francois;Rülicke, Thomas;Stoffel, Markus;
Nature Medicine 2015 Vol. 21 pp. 619-627
169
bengt-frederik2015naturethe

Abstract

The miR-200 family of miRNAs is upregulated in diabetes and leads to the apoptosis of pancreatic beta cells, while its knockout prevents this pathology

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