A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability
Abstract
The poly(A)-binding protein (PAB) gene of Saccharomyces cerevisiae is essential for cell growth. A 66-amino acid polypeptide containing half of a repeated N-terminal domain can replace the entire protein in vivo. Neither an octapeptide sequence conserved among eucaryotic RNA-binding proteins nor the …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
pubmed abstract
nih
national institutes of health
national library of medicine
research support
u.s. gov't
P.H.S.
carrier proteins / genetics
osmolar concentration
structure-activity relationship
cell division
binding sites
carrier proteins / metabolism*
cell survival
dna mutational analysis
poly a / metabolism*
r w davis
pmid:3313012
pmc367964
doi:10.1128/mcb.7.9.3268-3276.1987
a b sachs
r d kornberg
poly(a)-binding proteins
saccharomyces cerevisiae / physiology*
Access
Citation
ID:
270147
References
Blockchain Verification
Account:
NFT Contract Address:
0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
270147
Unique Identifier:
Network:
Scimatic Chain (ID: 481)
Loading...
Blockchain Readiness Checklist
Authors
Abstract
Journal Name
Year
Title
Creates 1,000,000 NFT tokens for this article
Token Features:
- ERC-1155 Standard NFT
- 1 Million Supply per Article
- Transferable via MetaMask
- Permanent Blockchain Record
Scan with Saymatik Web3.0 Wallet