Granulocyte Macrophage Colony-Stimulating Factor in 66 Patients with Myeloid or Lymphoid Neoplasms and Recipients of Hematopoietic Stem Cell Transplantation with Invasive Fungal Disease
Amar Safdar;Gilhen Rodriguez;Jorge Zuniga;Fadi Al Akhrass;Georgia Georgescu;Anupam Pande;
acta haematologica2013Vol. 129pp. 26-34
194
safdar2013actagranulocyte
Abstract
Background/Aims: Adding granulocyte macrophage colony-stimulating factor (GM-CSF) may improve the response to antifungal therapy in immunosuppressed patients with invasive fungal disease (IFD). Methods: We retrospectively assessed 66 patients in whom GM-CSF was given during antifungal therapy. Results: Severe neutropenia (77%) and refractory/relaps