Ghrelin is a growth-hormone-releasing acylated peptide from stomach
Kojima M;Hosoda H;Date Y;Nakazato M;Matsuo H;Kangawa K;;
Nature1999Vol. 402pp. -
376
m1999natureghrelin
Abstract
Small synthetic molecules called growth-hormone secretagogues (GHSs) stimulate the release of growth hormone (GH) from the pituitary. They act through GHS-R, a G-protein-coupled receptor for which the ligand is unknown. Recent cloning of GHS-R strongly suggests that an endogenous ligand for the rece …