Carcinogenic assessment of cobalt-containing alloys in medical devices or cobalt in occupational settings: A systematic review and meta-analysis of overall cancer risk from published epidemiologic studies
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Carcinogenic assessment of cobalt-containing alloys in medical devices or cobalt in occupational settings: A systematic review and meta-analysis of overall cancer risk from published epidemiologic studies

Zhang S;Holy CE;Eichenbaum G;Perkins LE;Hasgall P;Katz LB;Brown JR;Orlandini L;Fessel G;Nasseri-Aghbosh B;Egnot NS;Zhou M;Beech R;Marcello SR;Coplan PM;;
regulatory toxicology and pharmacology : rtp 2021 Vol. 125 pp. -
207
s2021regulatorycarcinogenic

Abstract

In 2020, the European Commission up-classified pure cobalt metal to a Category 1B hazard, based primarily on data from rodent inhalation carcinogenicity studies of metallic cobalt. The European Commission review did not evaluate cobalt-containing alloys in medical devices, which have very different …

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National Center for Biotechnology Information NCBI NLM MEDLINE pubmed abstract nih national institutes of health national library of medicine pmid:34229014 doi:10.1016/j.yrtph.2021.104987 shumin zhang chantal e holy paul m coplan

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